According to Skrekas, permits will not be needed anymore for 897 professions, which account for 14.3% of the Greek GDP.
A ministry official said it will help entrepreneurs start their businesses faster, without the hassle of going through several state agencies.
In the future, businesses will simply have to submit their papers to the General Commercial Registry (GEMI) and then follow set guidelines.
Skrekas said this would save entrepreneurs two to three months in filling out paperwork and waiting for replies.
Food, paper, wood and clothing are some of the industries that will benefit from the new regulations.
Electronics manufacturing, engineering, energy, repair services and retailers, as well as wholesalers are also included.